CXCR2 and neoplasm: CXCR2 is a chemokine receptor expressed in different types of cells including leukocytes (Cheng et al., 2019), tumor cells (Acosta and Gil, 2009), endothelial cells (Li et al., 2018), chondrocytes (Sherwood et al., 2015), and mesenchymal cells (Kwon et al., 2021).