EFEMP1 and neoplasm: For example, our data revealed that WNT7A, VEGFA, EFEMP1, TRPV2, and FOXC2 were significantly highly expressed in DBTRG, which was likely one of the molecular bases for the stronger invasion capacity of DBTRG, as previous studies have proved that upregulation of these genes could enhance the invasion ability of tumor cells (Li et al., 2013; Gong et al., 2014; Wang et al., 2015; Liu and Liu, 2018; Kato et al., 2022).