Multiple system atrophy Human cases from University of California San Diego Alzheimer Disease Research Center 5 transgenic mouse models (MBP1-hαsyn tg, MBP29-hαsyn tg, mThy1-hαsyn tg, mThy1-hAPP tg, mThy1-htau) and non-transgenic mice. The gene discussed is TG; the disease is multiple system atrophy.