There was a positive correlation between Hb level and handgrip strength in the Indonesian elderly population (r: 0.349; p value: 0.000). Multivariate analysis showed that anemia was significantly associated with weak handgrip strength (OR: 1.557; 95% CI: 1.314-1.846; p value: <0.001). This evidence concerns the gene GSTM1 and anemia.