EDN1 and androgen insensitivity syndrome: Compared with the healthy controls, the expression levels of ET-1 (124.35 ± 16.74 pg/ml versus 61.43 ± 6.81 pg/ml, p < 0.05) and VEGFA (416.04 ± 60.59 pg/ml versus 199.68 ± 25.16 pg/ml, p < 0.05) were markedly elevated in AIS patients (Figures 4A, B).