lncRNA CEBPA-AS1 (CCAAT enhancer-binding protein alpha, aka LOC80054), that is usually downregulated in osteosarcoma (GSE16088) and other cancers (Ke et al., 2017), has recently been reported to inhibit osteosarcoma cell proliferation, differentiation, and enhance apoptosis by repressing the Notch signaling pathway via upregulating the expression of miR-10b-5p-mediated nuclear receptor corepressor 2 (NCOR2) (Xia et al., 2020). This evidence concerns the gene CEBPA and osteosarcoma.