COQ8B and chronic kidney disease: Similar with our study, 20 patients (5.8%) with biallelic mutations of ADCK4 was screened for in the Chinese children with SRNS, non-nephrotic proteinuria, or CKD of unknown origin by Raojia et al. in 2020 (30), two mutations, namely c.737G>A (p.S246N) and c.748G>C (p.D250H), were the most prevalent in these two studies.