Cutaneous reaction to food is a common presentation of food allergy, including IgE-mediated (urticaria, angioedema, flushing, and pruritus), cell-mediated (contact dermatitis and dermatitis herpetiformis), and mixed IgE- and cell-mediated (atopic dermatitis) reactions (26). The gene discussed is IGHE; the disease is atopic eczema.