FBG and HbA1c respectively reflect the short- and long-term blood glucose level of diabetic patients, although the T2D had higher FBG and HbA1c levels compared with the T1D patients, the frequencies of Bregs, Tim-1+ Bregs and IL-10+ Bregs in the T2D appears not to be lower than that in the T1D. Here, IL10 is linked to type 1 diabetes mellitus.