Several NLRP3 inhibitors have been shown to inhibit inflammation caused by gouty arthritis, emphasizing the importance of NLRP3 as a target in treatments for gout (Lee H. G. et al., 2016; Ruiz-Miyazawa et al., 2017; Huang et al., 2018; Marchetti et al., 2018b; Lee H. E. et al., 2019; Deng et al., 2020). Here, NLRP3 is linked to gout.