NLRP3 inflammasome has also been suggested to play an important role in Parkinson’s disease (PD), a neurodegenerative disease characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta, where high levels of IL-1β have been detected in patients suffering from PD (Mogi et al., 1994; Antony et al., 2013; Tan et al., 2020). The gene discussed is IL1B; the disease is Parkinson disease.