lncRNA small nucleolar RNA host gene 3 (SNHG3) induces epithelial–mesenchymal transition (EMT) and sorafenib resistance by regulating the miR-128/cluster of differentiation 151 (CD151) pathway in HCC (Zhang et al., 2019), having the potential to affect necroptosis through different pathways such as H19-derived miR-675 targeting FAS-associated death domain protein (FADD) (Harari-Steinfeld et al., 2021). The gene discussed is FADD; the disease is hepatocellular carcinoma.