However, another study (Lv et al., 2014) has reported that miR141-CXCL1-CXCR2 signaling–induced Treg recruitment regulates the metastasis and survival of non–small cell lung cancer; therefore, the type of immune cells that CXCL1 recruits in the TIME should be further explored. This evidence concerns the gene CXCR2 and lung cancer.