Xu-Monette, Z. Y. et al. demonstrated the negative impact of PD‐1‐ and CD8‐positive T‐cells in cases of PD‐L1 positivity of lymphoma cells, and a high proportion of PD‐L1‐positive TME macrophages was linked to inferior outcomes (Xu-Monette et al., 2019). Here, CD274 is linked to lymphoma.