The strong risk association of HLA-DRB1*11:04 and HLA-DPB1*13:01 with SSc has been reported in multiple ethnic groups, enriched specifically in ATA + patients (Fanning et al., 1998; Arnett et al., 2010; Gourh et al., 2020; Acosta-Herrera et al., 2021). Here, HLA-DPB1 is linked to systemic sclerosis.