Both HLA-DRB1*11:04 and HLA-DPB1*13:01 alleles have been reported across a diversity of ethnic groups to be associated with SSc risk, and, specifically, ATA + disease (Zochling et al., 2014; Gourh et al., 2020; Acosta-Herrera et al., 2021). This evidence concerns the gene HLA-DRB1 and systemic sclerosis.