The Kaplan–Meier survival analyses demonstrated that the upregulation of Reptin was very strongly related to worse DSS in 20 types of cancer, including GBMLGG, LGG, LUAD, SARC, KIRP, KIPAN, PRAD, HNSC, LIHC, MESO, SKCM-M, SKCM, UVM, ACC, BLCA, BRCA, CHOL, KIRC, LUSC, and Stomach and Esophageal carcinoma (STES) (Figure 3B). Here, RUVBL2 is linked to cancer.