PRSS21 and neoplasm: Furthermore, we performed the LASSO regression analysis for the differential genes (Figures 3A,B), and obtained 21 genes as potential hub genes (LRMP, SDR42E1, ERICH5, NPPC, KCNJ3, CNTNAP2, LINC00346, CPVL, UNC93A, ONECUT2, MAGEA6, SLC19A3, DDC, VGF, LINC00392, AQP2, PRSS21, ETV4, F12, RAP2A, and GRTP1), suggesting a strong functional association of these genes with tumor epithelial cells.