METTL1 and intrahepatic cholangiocarcinoma: According to previous reports, Dai et al. (2021) identified that METTL1 overexpression was associated with poor prognosis in patients with intrahepatic cholangiocarcinoma, and they also found the carcinogenic role of METTL1-mediated m7G tRNA modification in promoting intrahepatic cholangiocarcinoma.