One important caveat of these analyses is the focus on relative proportions, which are not absolute cell counts (Mancarci et al., 2017; Toker et al., 2018); therefore, potentially paradoxical reported differences in some rCTPs here, such as greater L5 6 IT Car3 and L6b glutamatergic cell rCTPs in AD, may not necessarily indicate that these cell types are actually increasing in their absolute cell counts. The gene discussed is CA3; the disease is Alzheimer disease.