SCN5A and encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy: These include rodents with mutations in the SCN1A gene (mimics Dravet syndrome) (Scheffer and Nabbout, 2019), SCN5A gene (mimics Brugada syndrome), KCNH2, KCNQ1 genes (mimics Long QT syndrome), etc. (Tu et al., 2011).