AKT shows an increased trend in various fibrotic diseases (Lu et al., 2010; Huang et al., 2011), and it also increases in fibroblasts of bleomycin-induced IPF in vivo and in vitro (Vittal et al., 2005; Xia et al., 2008; Le Cras et al., 2010). Here, AKT1 is linked to idiopathic pulmonary fibrosis.