Several genes downregulated following SNX112 treatment, including CDC20, TPX2, CEP55, FOXM1, KIFC1, NUF2, BUB1B, BIRC5 and PLK1 were overexpressed in Papillary Renal Cell Carcinoma TCGA cohort (Suppl. The gene discussed is BUB1B; the disease is papillary renal cell carcinoma.