HSP90AA2P and gastrointestinal stromal tumor: The HSP90alpha/beta-specific inhibitor, TAS-116 (pimitespib) has recently been reported to meet its Phase 3 endpoint by significantly prolonging progression-free survival in patients with gastrointestinal stromal tumor refractory to imatinib, sunitinib and regorafenib in a Phase-III clinical trial [48]; (Len Neckers, personal communication, 2021), and merits evaluation in PRCC.