First, calcification in IPMN is likely to represent a unique and unrecognized form of calcifying obstructive pancreatitis caused by prolonged ductal obstruction by thick mucin, which has a propensity to build up calcium salt deposits and coexist with chronic calcifying pancreatitis [27, 28]. The gene discussed is MUC5AC; the disease is pancreatic intraductal papillary-mucinous neoplasm.