ITGA2B and Thrombocytopenia: Apart from that, history of cardiac surgery (P = 0.005), higher CRUSADE risk stratification (P = 0.009), elective operation (P = 0.004) and administration of bivalirudin combined with GP IIb/IIIa inhibitors (P = 0.005) were correlated with increased incidence of thrombocytopenia.