While there is an elevated RNASE4 level in prostate cancer tissue samples compared to BPH tissue samples (p = 0.0006), no differences were observed in RNASE4 levels between healthy controls and BPH samples (p = 0.3861), indicating the superior specificity of RNASE4 in prostate cancer diagnosis. The gene discussed is RNASE4; the disease is Familial prostate cancer.