RNASE4 and neoplasm: The tumor-bearing animals were separated into 3 groups according to tumor sizes so that each group had animals with matched tumor sizes, and treated with PBS (n = 12) or with RNASE4 mAb at 10 mg/kg (n = 6) or 30 mg/kg (n = 6), respectively, by i.p. injection once every 3 days for 39 days.