,37 Under hypoxia, HIF-1α accumulates, promotes the division and proliferation of vascular endothelial cells, induces angiogenesis and regeneration, inhibits inflammation after vascular endothelial cell injury, and maintains the function of cardiomyocytes.38, 39, 40 Myocardial hypoxia-ischemia is the main mechanism of myocardial infarction, and the degree of ischemia is different between STEMI and NSTEMI. Here, HIF1A is linked to ischemia.