These include: (1) laboratory findings including presence of an elevated anti-CCP, RF, and/or elevated CRP; (2) physical examination findings by the referring physician including symmetrical joint pain or joint swelling on exam, and presence of psoriasis (in case of psoriatic arthritis) (3) important items on history including morning stiffness lasting more than 30 min, symptoms lasting more than 6 weeks, and positive family history of RA. This evidence concerns the gene CRP and psoriasis.