CDKN2C and glioblastoma: However, diverse CDKN2C expression patterns (compared with those in non-cancer tissues) were detected in various cancers as follows: upregulated CDKN2C mRNA expression in ten cancers (CHOL, ESCA, GBM, HNSCC, KIRC, LIHC, LUAD, LUSC, STAD, and THCA) and downregulated mRNA expression in six cancers (BRCA, COAD, KICH, PRAD, READ, and UCEC).