Notably, based on the current clinical data of this study, multivariate Cox regression analysis indicated that CDKN2C expression was an independent prognosis (at least one of OS, DSS, DFI, and PFI) factor for eight of the 14 cancers listed above; and the eight cancers are CESC, KICH, LGG, LIHC, MESO, PRAD, THYM, and UVM (p < 0.05; Additional file 7). This evidence concerns the gene CDKN2C and cancer.