In addition, in CPP group, there was also a positive correlation (p < 0.05) between PTH concentrations and growth rate (r = 0.285), bone age (r = 0.539), basal estradiol (r = 0.288), basal FSH (r = 0.284), basal LH, (r = 0.412) and LH peak (r = 0.378). The gene discussed is PTH; the disease is central precocious puberty.