TMPRSS2 and viral infectious disease: Of the three epithelial segments that comprise the ocular surface epithelium, corneal epithelium has been shown to be resistant to SARS-CoV-2 infection (Miner et al., 2020), while the adjacent limbal epithelium, which harbors the corneal epithelial stem cells, expresses ACE2 and TMPRSS2 at high levels and appears permissive to viral infection (Eriksen et al., 2021).