The activation of cGAS-cGAMP-STING pathway not only plays a direct killing role in tumor cells, but also plays a crucial role in the activation of innate immunity (Ishikawa and Barber 2008; T. Li et al. 2016a, b; Pepin and Gantier 2017; Woo et al. 2014). The gene discussed is STING1; the disease is neoplasm.