Meanwhile, homozygous CNV analysis showed that FADD in 22 cancer types, FASLG in 25 cancer types, RIPK1 in 22 cancer types, TLR3 in 15 cancer types, TNF in 23 cancer types, FAS in 15 cancer types, MLKL in 12 cancer types, and RIPK3 in 17 cancer types had homozygous amplifications. Here, TNF is linked to cancer.