Survival analysis showed that CNVs of TNF in 22 cancer types, TLR3 in 10 cancer types, RIPK1 in 9 cancer types, FAS in 8 cancer types, FADD in 8 cancer types, RIPK3 in 7 cancer types, MLKL in 6 cancer types, and FASLG in 5 cancer types were significantly associated with overall prognosis (Figure 4E). This evidence concerns the gene TLR3 and cancer.