They found that a significant decrease in the percentage of OT-I CD8+ T cells infiltration at the tumor site and an increase in the percentage of OT-I CD8+ T cells infiltration in the tumor-targeted lymph nodes happened when researchers placed magnets near the tumor during relay loading of OT-I CD8+ T cells with APS-MNP, while no significant increase in the number of OT-I CD8+ T cells infiltrating into tumor sites has been observed after modifying them with APS-MNP. This evidence concerns the gene CD8A and neoplasm.