EGFR and neoplasm: Prior elegant work has shown that photo‐triggered release of irinotecan from porphyrin‐doped liposomes within the vasculature of subcutaneous PDAC tumors leads to enhanced tumor deposition of chemotherapy and improved outcomes.[43] In our study, the motivating feature of the TPMIL approach lies fundamentally in the molecular specific interactions with tumor receptor EGFR, and tumor cell co‐delivery of both BPD‐PC and irinotecan.