RPS6KB1 and autosomal dominant polycystic kidney disease: Similarly, treatment of ADPKD mice with 10 mg·kg−1 PF‐06409577 (Fig. 4B, G–I) resulted in significant AMPK phosphorylation (P = 0.0047, Student's t test, n = 3), down‐regulated p70S6K phosphorylation (P = 0.0273, Student's t test, n = 3) and 4EBP1 phosphorylation (P = 0.0009, Student's t test, n = 3).