Overexpression of protein arginine methyltransferase 5 (PRMT5) in malignant lung cells has to lead to the development of inhibitory molecules like GSK3326595,7 PRT811,8 and JNJ‐64619178,9 currently under investigation in advanced solid malignancies including NSCLC.10 Here, PRMT5 is linked to non-small cell lung carcinoma.