EGFR and chronic obstructive pulmonary disease: Our findings not only indicate that compared with CCRT, patients with EGFR-TKIs combined with TRT were more likely to develop symptomatic RP, but also identified that ilV30, tlV20, and presence of COPD had potential predictive values for the occurrence of symptomatic RP in this selected population, and the combination of these three factors was found to be meaningful.