It is also worth noting that those with a positivefirst round FIT result who did not undergo colonoscopy had a lower f-Hb profilein the second round but higher than in any of the other categories; this can beexplained by a larger proportion of those in this category continuing to harbourneoplastic pathology into the second round than those in whom neoplasia had beendetected and removed in the first round. Here, GSTM1 is linked to neoplasm.