Proteins related to apoptosis and also present in PCa exosomes, such as Bcl-2, inhibitor of apoptosis (IAP) and heat shock protein (HSP) and proteins related to cell metabolism, such as glucose transporter 1 (GLUT1) and Ras, etc. Considered a family of survivin proteins of tumor cells (180). The gene discussed is BIRC5; the disease is neoplasm.