detected the expression of Survivin in the tissues of 82 PCa patients and found that its expression was positively correlated with the pathological stage, Gleason score (ranges from 1-5 and describes how much the cancer from a biopsy looks like healthy tissue (lower score) or abnormal tissue (higher score)) and cell proliferation activity of PCa, and could inhibit cell apoptosis (58). This evidence concerns the gene BIRC5 and posterior cortical atrophy.