found a significant association between elevated glucosamine-6-Phosphate Deaminase 1 (GNPDA1) levels and advanced tumor stage, TNM (the TNM classification of malignant tumors) stage or grade, and the subsequent apoptotic staining analysis revealed that elevated GNPDA1 levels inhibited HCC cell apoptosis (104). This evidence concerns the gene GNPDA1 and neoplasm.