In HER2+ BC, HR of 2.17 in RPCB class I (95% CI: 1.14, 5.83), 7.41 of class II (95% CI: 3.49, 15.74), and 43.89 of class III (95% CI: 21.88, 88.02) (p <0.001) (Figure 3C). The gene discussed is ERBB2; the disease is breast cancer.