Analysis and comparison of clinical baseline data revealed that relative to control-obese subjects, obese PCOS patients presented with evident differences in BMI, Ferriman–Gallwey score, HOMA-IR, FINS, T, FSH, LH/FSH, TNF-α, and IL-6 levels (all P < 0.05, Table 2). The gene discussed is TNF; the disease is polycystic ovary syndrome.