Herein, our findings demonstrated that compared with healthy subjects, obese and non–obese PCOS patients presented with higher BMI, increased Ferriman–Gallwey score, in addition to elevated HOMA-IR, FINS, total T, LH/FSH, and TNF-α and IL-6 levels, and lower FSH levels. Here, BRD2 is linked to polycystic ovary syndrome.