In the present study, patients in the control group were treated with rupatadine fumarate alone for one month and its was found that their signs and symptoms were alleviated, and EOS, IgE levels, and inflammatory cytokines were all ameliorated, suggesting the outstanding clinical value of rupatadine fumarate in the treatment of allergic rhinitis, and the results are consistent with the previous studies. Here, IGHE is linked to allergic rhinitis.