Liver fibrosis between WT and Mettl3 cKO mice was also comparable, evidenced by RT-qPCR (Figure 6(f)) and western blot (Figure 6(g)) for profibrotic markers (Acta2 (encoding α-smooth muscle actin (αSMA)), Col1a1 (encoding collagen type I), and Pdgfrb (encoding Pdgfrβ)), H&E staining, PSR staining, and immunohistochemical staining for αSMA of mouse liver tissues (Figures 6(h)–6(j)). This evidence concerns the gene METTL3 and Hepatic fibrosis.