Finally, the expression values of GPC3, ACSM3, SPINK1, COL15A1, TP53I3, RRAGD, and CLDN10 in HCC samples were particularly lower than individuals in the control cohort (Figures 4(a)–4(c); all P < 0.05), while the expression values of GPR88 in HCC samples were not greatly higher than individuals in the control group in GSE14520-GPL3921 dataset and ICGC (P > 0.05). This evidence concerns the gene CLDN10 and hepatocellular carcinoma.