PANX1 and brain infarction: It is reported that target genes cacna1g, tpcn2, panx1, and Fyn are involved in pathophysiological processes such as neuroexcitatory conduction, autophagy, inflammation, and synaptic plasticity in cerebral infarction (Shin et al., 2008; Shestopalov and Slepak, 2014; Guo et al., 2020; Rajani et al., 2021).