RNASE1 and melanoma: Given the revealed ability of RNase A to significantly affect the expression of miRNAs, including miR-21a, miR-31, miR-145a, miR-155 and miR-10b, in B16 melanoma-bearing mice (Figure 7), we next questioned the expression of which genes can be regulated by these RNase-A-susceptible miRNAs and in what biological processes these genes can be involved.