Based on all the pathways given, SOD, NFKB, TGF beta, C-Myc, STAT3, Lamin-B2, Macrophage mannose receptor 1, and Histone H1.0 proteins attracted attention, which was also observed in RNA-seq, and they have also been implicated in mediating lung cancer (Table 3). This evidence concerns the gene STAT3 and lung cancer.