Among these, metabolic pathways (AMPK), immunological pathways (PD-L1), mitochondrial function (SOD), inflammation pathway (NFKB, STAT3, TGF beta), and apoptotic pathways (Lamin-B2, Macrophage mannose receptor 1) drew our attention because of their significance in cancer mediation shown in Figure 2. Here, STAT3 is linked to cancer.