Quebecol and some of its derivatives were also reported to have in vitro anti-inflammatory activity as shown by their inhibition of the secretion of proinflammatory cytokines (interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-α)) and the reduction in the activation of the NF-κB transcription factor in LPS-stimulated human macrophages, which are involved in the pathology of psoriasis [14]. This evidence concerns the gene TNF and psoriasis.