In addition, the cancer marker proteins related to proliferation and metastasis or migration, such as AXL, CA9, ENO2, HER1, HER2, HER3, PRGN, PDGF-AA, DKK1, CTSB, CTSD, BCLX, CSF1, and CAPG, were significantly downregulated by BP-LCNs. This evidence concerns the gene CA9 and cancer.