Several included publications investigated the genes involved in neurotransmission (COMT [65,74,80], serotonin receptors/transporters [55,62,73], dopamine receptors [64,73]), and in energy and lipid homeostasis (AMP-K related genes [54,56], HSD11β1 [58,59]), mostly regarding weight gain (or MetS). This evidence concerns the gene HSD11B1 and metabolic syndrome.