Polymorphisms within the ACE2 and ACE genes (ACE2 rs4240157, rs4646155, rs4830542, rs2074192 rs233575, rs2158083, and rs21068809, ACE G8790A, and I/D) were found to correlate with hypertension, and since the hypertension influences COVID-19 prognosis, the analysis of ACE2 polymorphisms in this group of patients may be of interest [128]. This evidence concerns the gene ACE and COVID-19.